![]() Until then, they are kept safe by specialized primary packaging solutions, protecting them from potential mechanical stress and contributing to high product quality. While the cryogenic freezer RoSS.LN2F is able to freeze products down to -180 ☌ in a controlled manner, stem cells are ready for cryopreservation with or without liquid nitrogen until the stem cells are due to be thawed and applied. The high-dose treatment kills the cancer cells, but it also gets rid of the blood-producing cells that are left in your bone marrow. You are then treated with high doses of chemotherapy. Additionally, Single Use Support's solutions for automated filling are able to deal even with minute units. In an autologous transplant, your own blood-forming stem cells are collected. Here is where Single Use Support comes into action: With an entire product line-up for ultra-cold freezing, storing and shipping, the demands of highly sensitive cell therapies in terms of temperature consistency can easily be met. In an autologous transplant, some of the patients own bone marrow or peripheral blood stem cells are removed and reserved. The process of freezing and thawing stem cells can be complex and requires specialized equipment and expertise. Proper storage is critical for maintaining the quality of the stem cells. Once the autologous stem cells are collected, they need to be stored until they are needed for transplantation. 2Īutologous Stem Cell Storage – A Matter of Temperature Additionally, if the patient's cancer cells are present in the collected stem cells, the transplant cannot be used in treating the cancer. ![]() This effect describes a donor’s immune cells fighting tumor cells in the patient’s body and can be achieved with allogeneic hematopoietic stem cell transplantation. However, one of the main disadvantages of autologous stem cell transplantation is that it does not provide the benefit of graft-versus-tumor effect. Because the patient's own stem cells are used, there is also a reduced risk of rejection by their immune system. The main advantage of autologous stem cell transplantation is that it does not involve the risk of graft-versus-host disease (GVHD), a potentially serious complication where the donor's immune cells attack the patient's healthy tissues. Both methods have advantages and disadvantages. Allogeneic transplantation involves the use of stem cells from a donor rather than the patient themselves. RoSS.KSET | Protecting small single-use bagsĪdvantages and Disadvantages Over Allogeneic Stem Cell TransplantationĪutologous stem cell transplantation is often compared to allogeneic stem cell transplantation.RoSS® Shell | Protecting single-use bags.End-to-End Liquid Transfer Single-Use Bag.Biopharmaceutical end-to-end solutions.
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